Record Information Version 1.0 Status Detected and Quantified Creation Date 2020-12-10 18:36:57 UTC Update Date 2022-08-31 06:06:49 UTC MiMeDB ID MMDBc0000402 Metabolite Identification Common Name 1-Phenylethylamine Description 1-Phenylethylamine, or alpha-phenethylamine, is an amine. Individual enantiomers of this basic compound are useful for performing chiral resolution of acidic compounds by forming diastereomeric salts. -- Wikipedia . Structure Synonyms Value Source 1-Amino-1-phenylethane ChEBI 1-Phenethylamine ChEBI alpha-Aminoethylbenzene ChEBI alpha-Methylbenzenemethanamine ChEBI alpha-Methylbenzylamine ChEBI alpha-Phenylethylamine ChEBI a-Aminoethylbenzene Generator Α-aminoethylbenzene Generator a-Methylbenzenemethanamine Generator Α-methylbenzenemethanamine Generator a-Methylbenzylamine Generator Α-methylbenzylamine Generator a-Phenylethylamine Generator Α-phenylethylamine Generator
Chemical Formula C8 H11 N Average Molecular Weight 121.1796 Monoisotopic Molecular Weight 121.089149357 IUPAC Name Not Available Traditional Name Not Available CAS Registry Number Not Available SMILES Not Available InChI Identifier InChI=1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3
InChI Key RQEUFEKYXDPUSK-UHFFFAOYSA-N Chemical Taxonomy Functional Ontology Not Available Physical Properties State Expected Solid Predicted Properties Not Available Spectra Not Available Biological Properties Cellular Locations Biospecimen Locations Blood
Cerebrospinal Fluid (CSF)
Feces
Urine Tissue Locations Not Available Associated OMIM IDs 114500 (Colorectal cancer)610247 (Eosinophilic esophagitis)Human Proteins and Enzymes Proteins #<MetaboliteProteinLink:0x000055b76e25d7c8> Human Pathways Pathways Metabolic Reactions Not Available
Health Effects and Bioactivity Health Outcome/Bioactivity Metabolite Response/Effect Related Health Condition Evidence Type Measured in Matrix Data Source Reference Parkinson's disease Slight Decrease This associated disease is originally imported from HMDB metabolite HMDB0002017 concentration id 17679 Association Human Blood 11197147 details
Microbial Sources Kingdom Phylum Total species Hosts and Body Sites Microbial Links Firmicutes 5 Human Feces Indirect association between microbiota composition and metabolites measured in host biospecimen
Exposure Sources Source Type Source Sub-type Species Data Source Reference Details
Host Biospecimen and Location Host and Biospecimen Status Mean Std Min Max Units Age Sex Health Condition Data Source Reference Human Detected and Quantified 0.0071 0.0045 Adult (>18 years old) Both Parkinson's disease HMDB 11197147 detailsHuman Detected and Quantified 0.014 0.0065 Adult (>18 years old) Both Normal HMDB 11197147 detailsHuman Detected and Quantified 0.14 0.027 Adult (>18 years old) Both Normal HMDB 6527139 detailsHuman Detected and Quantified 0.0070 0.002 Adult (>18 years old) Both Normal HMDB Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992. detailsHuman Feces Detected but not Quantified Adult (>18 years old) Both Normal HMDB 27543620 details
External Links HMDB ID Not Available DrugBank ID Not Available Phenol Explorer Compound ID Not Available FooDB ID Not Available KNApSAcK ID Not Available Chemspider ID Not Available KEGG Compound ID Not Available BioCyc ID Not Available BiGG ID Not Available Wikipedia Link 1-Phenylethylamine METLIN ID Not Available PubChem Compound Not Available PDB ID Not Available ChEBI ID 670 Food Biomarker Ontology Not Available References Synthesis Reference Not Available General References Miura Y: Plasma beta-phenylethylamine in Parkinson's disease. Kurume Med J. 2000;47(4):267-72. doi: 10.2739/kurumemedj.47.267. [PubMed:11197147 ] Samonina-Kosicka J, Kanska M: Mechanistic studies of reactions catalysed by diamine oxidase using isotope effects. Isotopes Environ Health Stud. 2013;49(3):357-64. doi: 10.1080/10256016.2013.825612. [PubMed:24117430 ]
