Record Information Version 1.0 Status Detected and Quantified Creation Date 2020-12-10 18:54:28 UTC Update Date 2022-08-31 06:12:07 UTC MiMeDB ID MMDBc0000765 Metabolite Identification Common Name Succinimide Description Succinimide, also known as butanimide, belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines that bear a C=O group at position 2 of the pyrrolidine ring. Succinimide has been identified in urine (PMID: 22409530 ). Structure Synonyms Value Source 2,5-Diketopyrrolidine ChEBI 2,5-Dioxopyrrolidine ChEBI 2,5-Pyrrolidinedione ChEBI 3,4-Dihydropyrrole-2,5-dione ChEBI Butanimide ChEBI Dihydro-3-pyrroline-2,5-dione ChEBI Succinic acid imide ChEBI Succinic imide ChEBI Succinimide pharbiol Kegg Succinate imide Generator Succinimide HMDB
Chemical Formula C4 H5 NO2 Average Molecular Weight 99.089 Monoisotopic Molecular Weight 99.032028405 IUPAC Name Not Available Traditional Name Not Available CAS Registry Number Not Available SMILES Not Available InChI Identifier InChI=1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)
InChI Key KZNICNPSHKQLFF-UHFFFAOYSA-N Chemical Taxonomy Description Belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring. Kingdom Organic compounds Super Class Organoheterocyclic compounds Class Pyrrolidines Sub Class Pyrrolidones Direct Parent Pyrrolidine-2-ones Alternative Parents Substituents 2-pyrrolidone
Carboxylic acid imide
Dicarboximide
Carboxylic acid imide, n-unsubstituted
Lactam
Carboxylic acid derivative
Azacycle
Carbonyl group
Organooxygen compound
Organonitrogen compound
Hydrocarbon derivative
Organic oxide
Organopnictogen compound
Organic oxygen compound
Organic nitrogen compound
Aliphatic heteromonocyclic compound Molecular Framework Aliphatic heteromonocyclic compounds External Descriptors Functional Ontology Not Available Physical Properties State Expected Solid Predicted Properties Not Available Spectra Not Available Biological Properties Cellular Locations Not Available Biospecimen Locations Tissue Locations Not Available Associated OMIM IDs 114500 (Colorectal cancer)610247 (Eosinophilic esophagitis)Human Proteins and Enzymes Proteins Human Pathways Pathways Metabolic Reactions Not Available
Health Effects and Bioactivity Health Outcome/Bioactivity Metabolite Response/Effect Related Health Condition Evidence Type Measured in Matrix Data Source Reference
Microbial Sources Kingdom Phylum Total species Hosts and Body Sites Microbial Links Firmicutes 1 Human Feces Indirect association between microbiota composition and metabolites measured in host biospecimen
Exposure Sources Source Type Source Sub-type Species Data Source Reference Details
Host Biospecimen and Location Host and Biospecimen Status Mean Std Min Max Units Age Sex Health Condition Data Source Reference Human Urine Detected but not Quantified Not Specified Not Specified Normal HMDB 22409530 detailsHuman Detected but not Quantified HMDB details
External Links HMDB ID Not Available DrugBank ID Not Available Phenol Explorer Compound ID Not Available FooDB ID Not Available KNApSAcK ID Not Available Chemspider ID 10955 KEGG Compound ID C07273 BioCyc ID Not Available BiGG ID Not Available Wikipedia Link Succinimide METLIN ID Not Available PubChem Compound Not Available PDB ID Not Available ChEBI ID 9307 Food Biomarker Ontology Not Available References Synthesis Reference Not Available General References Zhang T, Creek DJ, Barrett MP, Blackburn G, Watson DG: Evaluation of coupling reversed phase, aqueous normal phase, and hydrophilic interaction liquid chromatography with Orbitrap mass spectrometry for metabolomic studies of human urine. Anal Chem. 2012 Feb 21;84(4):1994-2001. doi: 10.1021/ac2030738. Epub 2012 Feb 1. [PubMed:22409530 ]
