Record Information Version 1.0 Status Detected and Quantified Creation Date 2020-12-10 18:54:29 UTC Update Date 2022-08-31 06:12:08 UTC MiMeDB ID MMDBc0000766 Metabolite Identification Common Name Lanthionine Description Lanthionine belongs to the class of organic compounds known as L-cysteine-S-conjugates. These are compounds containing L-cysteine where the thio-group is conjugated. Lanthionine is a uremic toxin (PMID: 30087103 ). Structure Synonyms Not Available Chemical Formula C6 H12 N2 O4 S Average Molecular Weight 208.23 Monoisotopic Molecular Weight 208.051778048 IUPAC Name Not Available Traditional Name Not Available CAS Registry Number Not Available SMILES Not Available InChI Identifier InChI=1S/C6H12N2O4S/c7-3(5(9)10)1-13-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI Key DWPCPZJAHOETAG-IMJSIDKUSA-N Chemical Taxonomy Functional Ontology Not Available Physical Properties State Expected Solid Predicted Properties Not Available Spectra Not Available Biological Properties Cellular Locations Not Available Biospecimen Locations Tissue Locations Not Available Associated OMIM IDs 114500 (Colorectal cancer)610247 (Eosinophilic esophagitis)Human Proteins and Enzymes Proteins #<MetaboliteProteinLink:0x000055b76dee9560> Human Pathways Pathways Metabolic Reactions Not Available
Health Effects and Bioactivity Health Outcome/Bioactivity Metabolite Response/Effect Related Health Condition Evidence Type Measured in Matrix Data Source Reference
Microbial Sources Kingdom Phylum Total species Hosts and Body Sites Microbial Links Firmicutes 1 Indirect association between microbiota composition and metabolites measured in host biospecimen
Exposure Sources Source Type Source Sub-type Species Data Source Reference Details
Host Biospecimen and Location Host and Biospecimen Status Mean Std Min Max Units Age Sex Health Condition Data Source Reference Human Urine Detected but not Quantified Adult (>18 years old) Both Normal HMDB 30087103 detailsHuman Detected but not Quantified HMDB details
External Links External Links Not Available References Synthesis Reference Not Available General References Mair RD, Sirich TL, Plummer NS, Meyer TW: Characteristics of Colon-Derived Uremic Solutes. Clin J Am Soc Nephrol. 2018 Sep 7;13(9):1398-1404. doi: 10.2215/CJN.03150318. Epub 2018 Aug 7. [PubMed:30087103 ]
