Showing metabocard for Ubiquinol-8 (MMDBc0029540)

Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-17 23:31:33 UTC
Update Date2022-08-31 13:42:53 UTC
MiMeDB IDMMDBc0029540
Metabolite Identification
Common NameUbiquinol-8
DescriptionUbiquinol-8 is a member of the chemical class known as Polyprenylbenzoquinols. They are reduced forms of polyprenylbenzoquinines (ubiquinones). These are compounds containing a polyisoprene chain attached to a quinol at the second ring position. Ubiquiol-1 has 8 isoprene units. Normally in E. coli the active form of Ubiquinol has 8 isoprene units (Ubiquinol-8) and in humans it normally has 10. Coenzyme Q(n) exists in three redox states, fully oxidized (ubiquinone), partially reduced (semiquinones or ubisemiquinones), and fully reduced (ubiquinols). The redox functions of ubiquinol in cellular energy production and antioxidant protection are based on the ability to exchange two electrons in a redox cycle between ubiquinol (reduced) and the ubiquinone (oxidized) form. Ubiquionols are important in cellular respiration. They are fat-soluble and therefore mobile in cellular membranes; they play a unique role in the electron transport chain (ETC). In the inner bacterial membrane, electrons from NADH and succinate pass through the ETC to the oxygen, which is then reduced to water. The transfer of electrons through ETC results in the pumping of H+ across the membrane creating a proton gradient across the membrane, which is used by ATP synthase (located on the membrane) to generate ATP.
Structure
MOLSDFPDBSMILESInChI

MOL for #<Metabolite:0x000055b76d28bac0>

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3D MOL for #<Metabolite:0x000055b76d28bac0>

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3D SDF for #<Metabolite:0x000055b76d28bac0>

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3D-SDF for #<Metabolite:0x000055b76d28bac0>

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PDB for #<Metabolite:0x000055b76d28bac0>

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3D PDB for #<Metabolite:0x000055b76d28bac0>

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SMILES for #<Metabolite:0x000055b76d28bac0>

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INCHI for #<Metabolite:0x000055b76d28bac0>

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SynonymsNot Available
Chemical FormulaC49H78O4
Average Molecular Weight731.1412
Monoisotopic Molecular Weight730.590010984
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry NumberNot Available
SMILESNot Available
InChI Identifier
InChI=1S/C49H78O4/c1-36(2)20-13-21-37(3)22-14-23-38(4)24-15-25-39(5)26-16-27-40(6)28-17-29-41(7)30-18-31-42(8)32-19-33-43(9)34-35-45-44(10)46(50)48(52-11)49(53-12)47(45)51/h20,22,24,26,28,30,32,34,46-47,50-51H,13-19,21,23,25,27,29,31,33,35H2,1-12H3/b37-22+,38-24+,39-26+,40-28+,41-30+,42-32+,43-34+
InChI KeyFLVUMORHBJZINO-SGHXUWJISA-N