MiMeDB: Showing metabocard for Sorbitol-6-phosphate (MMDBc0029642)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:35:47 UTC

Update Date

2022-08-31 14:15:52 UTC

MiMeDB ID

MMDBc0029642

Metabolite Identification

Common Name

Sorbitol-6-phosphate

Description

Sorbitol 6-phosphate (Sor6P) is an intermediate in sorbitol biosynthesis. It is a competitive inhibitor for both cytosolic and chloroplastic PGIs with a K(i) of 61 and 40muM, respectively. PMID: 18242768

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₆H₁₅O₉P

Average Molecular Weight

262.1517

Monoisotopic Molecular Weight

262.04536859

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

20479-58-7

SMILES

Not Available

InChI Identifier

InChI=1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)

InChI Key

GACTWZZMVMUKNG-UHFFFAOYSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Blood

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

#<MetaboliteProteinLink:0x000055b76df08a00>

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Data Source	Reference
Prostate cancer		This associated disease is originally imported from HMDB metabolite HMDB0005831 concentration id 57636	Association	Human Blood		19212411	details

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
	Proteobacteria	1	Human	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	0.5		0.0	1.0		Adult (>18 years old)	Both	Prostate Cancer	HMDB	19212411	details

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Zhou R, Cheng L: Competitive inhibition of phosphoglucose isomerase of apple leaves by sorbitol 6-phosphate. J Plant Physiol. 2008 Jun 16;165(9):903-10. doi: 10.1016/j.jplph.2007.12.002. Epub 2008 Feb 1. [PubMed:18242768 ]

Showing metabocard for Sorbitol-6-phosphate (MMDBc0029642)

MOL for #<Metabolite:0x000055b76ba80048>

3D MOL for #<Metabolite:0x000055b76ba80048>

3D SDF for #<Metabolite:0x000055b76ba80048>

3D-SDF for #<Metabolite:0x000055b76ba80048>

PDB for #<Metabolite:0x000055b76ba80048>

3D PDB for #<Metabolite:0x000055b76ba80048>

SMILES for #<Metabolite:0x000055b76ba80048>

INCHI for #<Metabolite:0x000055b76ba80048>

Structure for #<Metabolite:0x000055b76ba80048>

3D Structure for #<Metabolite:0x000055b76ba80048>