MiMeDB: Showing metabocard for Sorbitol-6-phosphate (MMDBc0029642)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:35:47 UTC

Update Date

2022-08-31 14:15:52 UTC

Metabolite ID

MMDBc0029642

Metabolite Identification

Common Name

Sorbitol-6-phosphate

Description

Sorbitol 6-phosphate (Sor6P) is an intermediate in sorbitol biosynthesis. It is a competitive inhibitor for both cytosolic and chloroplastic PGIs with a K(i) of 61 and 40muM, respectively. PMID: 18242768

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₆H₁₅O₉P

Average Mass

262.1517

Monoisotopic Mass

262.04536859

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

20479-58-7

SMILES

Not Available

InChI Identifier

InChI=1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)

InChI Key

GACTWZZMVMUKNG-UHFFFAOYSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Blood

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0191880	Glucokinase	Enzyme	P35557	Homo_sapiens
MMDBp0191882	Hexokinase-3	Enzyme	P52790	Homo_sapiens
MMDBp0191883	Hexokinase-2	Enzyme	P52789	Homo_sapiens

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference
Prostate cancer		Association	Human Blood	HMDB	19212411

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	1	Human ; Human feces; Human feces; pleural fluid plaque; bal	Unknown

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	0.5		0.0	1.0		Adult (>18 years old)	Both	Prostate Cancer	HMDB	19212411

External Links

Not Available

General References

Zhou R, Cheng L: Competitive inhibition of phosphoglucose isomerase of apple leaves by sorbitol 6-phosphate. J Plant Physiol. 2008 Jun 16;165(9):903-10. doi: 10.1016/j.jplph.2007.12.002. Epub 2008 Feb 1. [PubMed:18242768 ]

Showing metabocard for Sorbitol-6-phosphate (MMDBc0029642)

MOL for #<Metabolite:0x00007f1240435018>

3D MOL for #<Metabolite:0x00007f1240435018>

3D SDF for #<Metabolite:0x00007f1240435018>

3D-SDF for #<Metabolite:0x00007f1240435018>

PDB for #<Metabolite:0x00007f1240435018>

3D PDB for #<Metabolite:0x00007f1240435018>

SMILES for #<Metabolite:0x00007f1240435018>

INCHI for #<Metabolite:0x00007f1240435018>

Structure for #<Metabolite:0x00007f1240435018>

3D Structure for #<Metabolite:0x00007f1240435018>