MiMeDB: Showing metabocard for O-Acetylserine (MMDBc0029701)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:38:07 UTC

Update Date

2022-08-31 17:12:47 UTC

Metabolite ID

MMDBc0029701

Metabolite Identification

Common Name

O-Acetylserine

Description

O-Acetylserine is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. O-Acetylserine is biosynthesized by acetylation of the serine by the enzyme serine transacetylase. The enzyme O-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releaseing acetate.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₅H₉NO₄

Average Mass

147.1293

Monoisotopic Mass

147.053157781

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

5147-00-2

SMILES

Not Available

InChI Identifier

InChI=1S/C5H9NO4/c1-3(7)10-2-4(6)5(8)9/h4H,2,6H2,1H3,(H,8,9)/t4-/m0/s1

InChI Key

VZXPDPZARILFQX-BYPYZUCNSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Biological Properties

Cellular Locations

Cytoplasm

Biospecimen Locations

Blood
Prostate
Urine

Tissue Locations

Prostate

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	1	Human ; Human feces; Human feces; pleural fluid plaque; bal	Unknown

Exposure Sources

Food Exposures

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	24.7	Adult (>18 years old)	Both	Normal	HMDB	21388201
Human Prostate	Detected but not Quantified		Not Specified	Not Specified	Normal	HMDB	34986597
Human	Detected but not Quantified					HMDB

External Links

Not Available

General References

Sugahara K, Zhang J, Kodama H: Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine. J Chromatogr B Biomed Appl. 1994 Jul 1;657(1):15-21. doi: 10.1016/0378-4347(94)80064-2. [PubMed:7952062 ]
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]

Showing metabocard for O-Acetylserine (MMDBc0029701)

MOL for #<Metabolite:0x00007f122179c4a0>

3D MOL for #<Metabolite:0x00007f122179c4a0>

3D SDF for #<Metabolite:0x00007f122179c4a0>

3D-SDF for #<Metabolite:0x00007f122179c4a0>

PDB for #<Metabolite:0x00007f122179c4a0>

3D PDB for #<Metabolite:0x00007f122179c4a0>

SMILES for #<Metabolite:0x00007f122179c4a0>

INCHI for #<Metabolite:0x00007f122179c4a0>

Structure for #<Metabolite:0x00007f122179c4a0>

3D Structure for #<Metabolite:0x00007f122179c4a0>