MiMeDB: Showing metabocard for O-Acetylserine (MMDBc0029701)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:38:07 UTC

Update Date

2022-08-31 17:12:47 UTC

MiMeDB ID

MMDBc0029701

Metabolite Identification

Common Name

O-Acetylserine

Description

O-Acetylserine is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. O-Acetylserine is biosynthesized by acetylation of the serine by the enzyme serine transacetylase. The enzyme O-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releaseing acetate.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₅H₉NO₄

Average Molecular Weight

147.1293

Monoisotopic Molecular Weight

147.053157781

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

5147-00-2

SMILES

Not Available

InChI Identifier

InChI=1S/C5H9NO4/c1-3(7)10-2-4(6)5(8)9/h4H,2,6H2,1H3,(H,8,9)/t4-/m0/s1

InChI Key

VZXPDPZARILFQX-BYPYZUCNSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Cytoplasm

Biospecimen Locations

Blood
Prostate
Urine

Tissue Locations

Prostate

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Data Source	Reference

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
	Proteobacteria	1	Human	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details
Plant	Fruit	Citrullus lanatus	FooDB	31437929	details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	24.7	Adult (>18 years old)	Both	Normal	HMDB	21388201	details
Human Prostate	Detected but not Quantified		Not Specified	Not Specified	Normal	HMDB	34986597	details
Human	Detected but not Quantified					HMDB		details

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Sugahara K, Zhang J, Kodama H: Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine. J Chromatogr B Biomed Appl. 1994 Jul 1;657(1):15-21. doi: 10.1016/0378-4347(94)80064-2. [PubMed:7952062 ]
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]

Showing metabocard for O-Acetylserine (MMDBc0029701)

MOL for #<Metabolite:0x000055b76dd18330>

3D MOL for #<Metabolite:0x000055b76dd18330>

3D SDF for #<Metabolite:0x000055b76dd18330>

3D-SDF for #<Metabolite:0x000055b76dd18330>

PDB for #<Metabolite:0x000055b76dd18330>

3D PDB for #<Metabolite:0x000055b76dd18330>

SMILES for #<Metabolite:0x000055b76dd18330>

INCHI for #<Metabolite:0x000055b76dd18330>

Structure for #<Metabolite:0x000055b76dd18330>

3D Structure for #<Metabolite:0x000055b76dd18330>