MiMeDB: Showing metabocard for Selenocystathionine (MMDBc0029826)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:43:18 UTC

Update Date

2022-12-15 22:51:48 UTC

Metabolite ID

MMDBc0029826

Metabolite Identification

Common Name

Selenocystathionine

Description

Selenocystathionine is formed from selenohomocysteine by the enzyme cystathionine beta-synthase (EC 4.2.1.22), as a by-product of cystathionine synthesis. It is an intermediate in selenoamine acid metabolism.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₇H₁₄N₂O₄Se

Average Mass

269.16

Monoisotopic Mass

270.011878774

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

2196-58-9

SMILES

Not Available

InChI Identifier

InChI=1S/C7H14N2O4Se/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)

InChI Key

ZNWYDQPOUQRDLY-UHFFFAOYSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Biological Properties

Cellular Locations

Cytoplasm

Biospecimen Locations

Feces

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Bacteria	Proteobacteria	38	Human ; Human feces; Human feces; pleural fluid plaque; bal	Unknown; Metabolic reconstruction
Bacteria	Firmicutes	78	Human feces; Human	Metabolic reconstruction
Bacteria	Actinobacteria	27	Human feces; Human	Metabolic reconstruction
Bacteria	Bacteroidetes	6	Human feces; Human	Metabolic reconstruction
Archaea	Euryarchaeota	1	Human feces	Metabolic reconstruction
Eukaryota/Fungi	Ascomycota	1	Human feces	Unknown

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB

External Links

Not Available

General References

Esaki N, Nakamura T, Tanaka H, Suzuki T, Morino Y, Soda K: Enzymatic synthesis of selenocysteine in rat liver. Biochemistry. 1981 Jul 21;20(15):4492-6. doi: 10.1021/bi00518a039. [PubMed:6456763 ]
Neuhierl B, Thanbichler M, Lottspeich F, Bock A: A family of S-methylmethionine-dependent thiol/selenol methyltransferases. Role in selenium tolerance and evolutionary relation. J Biol Chem. 1999 Feb 26;274(9):5407-14. doi: 10.1074/jbc.274.9.5407. [PubMed:10026151 ]
Freeman JL, Zhang LH, Marcus MA, Fakra S, McGrath SP, Pilon-Smits EA: Spatial imaging, speciation, and quantification of selenium in the hyperaccumulator plants Astragalus bisulcatus and Stanleya pinnata. Plant Physiol. 2006 Sep;142(1):124-34. doi: 10.1104/pp.106.081158. Epub 2006 Aug 18. [PubMed:16920881 ]

Showing metabocard for Selenocystathionine (MMDBc0029826)

MOL for #<Metabolite:0x0000560be29296d8>

3D MOL for #<Metabolite:0x0000560be29296d8>

3D SDF for #<Metabolite:0x0000560be29296d8>

3D-SDF for #<Metabolite:0x0000560be29296d8>

PDB for #<Metabolite:0x0000560be29296d8>

3D PDB for #<Metabolite:0x0000560be29296d8>

SMILES for #<Metabolite:0x0000560be29296d8>

INCHI for #<Metabolite:0x0000560be29296d8>

Structure for #<Metabolite:0x0000560be29296d8>

3D Structure for #<Metabolite:0x0000560be29296d8>