MiMeDB: Showing metabocard for O-Phospho-4-hydroxy-L-threonine (MMDBc0029840)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-17 23:43:48 UTC

Update Date

2022-08-31 17:19:14 UTC

MiMeDB ID

MMDBc0029840

Metabolite Identification

Common Name

O-Phospho-4-hydroxy-L-threonine

Description

O-Phospho-4-hydroxy-L-threonine is involved in the vitamin B6 metabolism system. O-Phospho-4-hydroxy-L-threonine is a precursor for pyridoxine. O-Phospho-4-hydroxy-L-threonine can be converted to 4-hydroxy-L-threonine and 2-Amino-3-oxo-4-phosphonooxybutyrate by threonine synthase [EC:4.2.3.1] and 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262], respectively.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₄H₁₀NO₇P

Average Molecular Weight

215.0985

Monoisotopic Molecular Weight

215.019488191

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C4H10NO7P/c5-3(4(7)8)2(6)1-12-13(9,10)11/h2-3,6H,1,5H2,(H,7,8)(H2,9,10,11)/t2-,3+/m1/s1

InChI Key

FKHAKIJOKDGEII-GBXIJSLDSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Feces

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

#<MetaboliteProteinLink:0x000055b76df9cac0>

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Data Source	Reference

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
	Proteobacteria	163	Human Feces; Human ; Pig	Unknown; Metabolic reconstruction
	Verrucomicrobia	1	Human	Metabolic reconstruction
	Bacteroidetes	116	Human Feces; Human	Metabolic reconstruction
	Synergistetes	1		Metabolic reconstruction
	Firmicutes	76	Human Feces; Human ; Cattle	Metabolic reconstruction
	Actinobacteria	21	Human Feces; Human	Metabolic reconstruction
	Fusobacteria	12	Human Feces; Human	Metabolic reconstruction
	Planctomycetes	1	Human Feces	Metabolic reconstruction
Fungi	Ascomycota	1	Human Feces	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB		details

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Noronha A, Modamio J, Jarosz Y, Guerard E, Sompairac N, Preciat G, Danielsdottir AD, Krecke M, Merten D, Haraldsdottir HS, Heinken A, Heirendt L, Magnusdottir S, Ravcheev DA, Sahoo S, Gawron P, Friscioni L, Garcia B, Prendergast M, Puente A, Rodrigues M, Roy A, Rouquaya M, Wiltgen L, Zagare A, John E, Krueger M, Kuperstein I, Zinovyev A, Schneider R, Fleming RMT, Thiele I: The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992. [PubMed:30371894 ]
Wishart DS, Li C, Marcu A, Badran H, Pon A, Budinski Z, Patron J, Lipton D, Cao X, Oler E, Li K, Paccoud M, Hong C, Guo AC, Chan C, Wei W, Ramirez-Gaona M: PathBank: a comprehensive pathway database for model organisms. Nucleic Acids Res. 2020 Jan 8;48(D1):D470-D478. doi: 10.1093/nar/gkz861. [PubMed:31602464 ]

Showing metabocard for O-Phospho-4-hydroxy-L-threonine (MMDBc0029840)

MOL for #<Metabolite:0x000055b76dee7f08>

3D MOL for #<Metabolite:0x000055b76dee7f08>

3D SDF for #<Metabolite:0x000055b76dee7f08>

3D-SDF for #<Metabolite:0x000055b76dee7f08>

PDB for #<Metabolite:0x000055b76dee7f08>

3D PDB for #<Metabolite:0x000055b76dee7f08>

SMILES for #<Metabolite:0x000055b76dee7f08>

INCHI for #<Metabolite:0x000055b76dee7f08>

Structure for #<Metabolite:0x000055b76dee7f08>

3D Structure for #<Metabolite:0x000055b76dee7f08>