Record Information Version 1.0 Status Detected and Quantified Creation Date 2021-11-18 00:05:52 UTC Update Date 2022-08-31 17:49:51 UTC MiMeDB ID MMDBc0030377 Metabolite Identification Common Name Phosphonoacetate Description A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. Structure Synonyms Not Available Chemical Formula C2 H5 O5 P Average Molecular Weight 140.0319 Monoisotopic Molecular Weight 139.987459782 IUPAC Name Not Available Traditional Name Not Available CAS Registry Number 4408-78-0 SMILES Not Available InChI Identifier InChI=1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7)
InChI Key XUYJLQHKOGNDPB-UHFFFAOYSA-N Chemical Taxonomy Functional Ontology Not Available Physical Properties State Solid Predicted Properties Not Available Spectra Not Available Biological Properties Cellular Locations Biospecimen Locations Tissue Locations Associated OMIM IDs 114500 (Colorectal cancer)610247 (Eosinophilic esophagitis)Human Proteins and Enzymes Proteins Human Pathways Pathways Metabolic Reactions Reaction ID Precursor Product Enzyme Reaction Type Data Source Reference
Health Effects and Bioactivity Health Outcome/Bioactivity Metabolite Response/Effect Related Health Condition Evidence Type Measured in Matrix Data Source Reference
Microbial Sources Kingdom Phylum Total species Hosts and Body Sites Microbial Links Proteobacteria 5 Human Unknown; Fungi Ascomycota 1
Exposure Sources Source Type Source Sub-type Species Data Source Reference Details
Host Biospecimen and Location Host and Biospecimen Status Mean Std Min Max Units Age Sex Health Condition Data Source Reference Human Fibroblasts Detected but not Quantified Not Specified Not Specified Normal HMDB 34986597 details
External Links External Links Not Available References Synthesis Reference Not Available General References Sairenji T, Hinuma Y, Sekizawa T, Yoshida M: Appearance of early and late components of Epstein-Barr virus-associated membrane antigen in Daudi cells superinfected with P3HR-1 virus. J Gen Virol. 1978 Jan;38(1):111-20. doi: 10.1099/0022-1317-38-1-111. [PubMed:202665 ] Abendroth A, Lin I, Slobedman B, Ploegh H, Arvin AM: Varicella-zoster virus retains major histocompatibility complex class I proteins in the Golgi compartment of infected cells. J Virol. 2001 May;75(10):4878-88. doi: 10.1128/JVI.75.10.4878-4888.2001. [PubMed:11312359 ]
