MiMeDB: Showing metabocard for PG(14:0/19:iso) (MMDBc0031478)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-18 00:50:43 UTC

Update Date

2022-08-31 18:11:11 UTC

MiMeDB ID

MMDBc0031478

Metabolite Identification

Common Name

PG(14:0/19:iso)

Description

PG(14:0/19:iso) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(14:0/19:iso), in particular, consists of one tetradecanoyl chain to the C-1 atom, and one 17-methylocatdecanoyl to the C-2 atom. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₃₉H₇₇O₁₀P

Average Molecular Weight

736.9964

Monoisotopic Molecular Weight

736.525435196

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C39H77O10P/c1-4-5-6-7-8-9-13-17-20-23-26-29-38(42)46-33-37(34-48-50(44,45)47-32-36(41)31-40)49-39(43)30-27-24-21-18-15-12-10-11-14-16-19-22-25-28-35(2)3/h35-37,40-41H,4-34H2,1-3H3,(H,44,45)

InChI Key

INAGBPCVOKEIFY-UHFFFAOYSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Not Available

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Data Source	Reference

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
	Proteobacteria	1	Human	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Casadei MA, Manas P, Niven G, Needs E, Mackey BM: Role of membrane fluidity in pressure resistance of Escherichia coli NCTC 8164. Appl Environ Microbiol. 2002 Dec;68(12):5965-72. doi: 10.1128/AEM.68.12.5965-5972.2002. [PubMed:12450817 ]
Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M: KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 2012 Jan;40(Database issue):D109-14. doi: 10.1093/nar/gkr988. Epub 2011 Nov 10. [PubMed:22080510 ]

Showing metabocard for PG(14:0/19:iso) (MMDBc0031478)

MOL for #<Metabolite:0x000055b76d09b580>

3D MOL for #<Metabolite:0x000055b76d09b580>

3D SDF for #<Metabolite:0x000055b76d09b580>

3D-SDF for #<Metabolite:0x000055b76d09b580>

PDB for #<Metabolite:0x000055b76d09b580>

3D PDB for #<Metabolite:0x000055b76d09b580>

SMILES for #<Metabolite:0x000055b76d09b580>

INCHI for #<Metabolite:0x000055b76d09b580>

Structure for #<Metabolite:0x000055b76d09b580>

3D Structure for #<Metabolite:0x000055b76d09b580>