Showing metabocard for (2Z)-2-aminobut-2-enoate (MMDBc0032127)
Record Information
Version
1.0
Status
Detected and Quantified
Creation Date
2021-11-18 02:03:31 UTC
Update Date
2022-08-31 18:30:44 UTC
MiMeDB ID
MMDBc0032127
Metabolite Identification
Common Name
(2Z)-2-aminobut-2-enoate
Description
(2Z)-2-aminobut-2-enoate is an intermediate of pathways L-threonine degradation I and L-isoleucine biosynthesis I in E. coli. It is a product for enzymes threonine dehydratase and threonine deaminase which catalyze the reaction L-threonine -> (2Z)-2-aminobut-2-enoate + H2O + H+ in both pathways. (2Z)-2-aminobut-2-enoate is also a substrate of the spontaneous reaction (2Z)-2-aminobut-2-enoate -> 2-iminobutanoate in both pathways (BioCyc compound: CPD-15056).
Belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
Wishart DS, Li C, Marcu A, Badran H, Pon A, Budinski Z, Patron J, Lipton D, Cao X, Oler E, Li K, Paccoud M, Hong C, Guo AC, Chan C, Wei W, Ramirez-Gaona M: PathBank: a comprehensive pathway database for model organisms. Nucleic Acids Res. 2020 Jan 8;48(D1):D470-D478. doi: 10.1093/nar/gkz861. [PubMed:31602464 ]