Showing metabocard for D-fructose 1-phosphate (MMDBc0033083)

Record Information
Version1.0
StatusDetected and Quantified
Creation Date2021-11-19 04:34:01 UTC
Update Date2022-12-15 22:51:53 UTC
MiMeDB IDMMDBc0033083
Metabolite Identification
Common NameD-fructose 1-phosphate
DescriptionFructose 1-phosphate, also known as D-fructose-1-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Metabolism of fructose thus essentially results in intermediates of glycolysis. The final product of glycolysis (pyruvate) may then undergo gluconeogenesis, enter the TCA cycle or be stored as fatty acids. Fructose 1-phosphate exists in all living organisms, ranging from bacteria to humans. Within humans, fructose 1-phosphate participates in a number of enzymatic reactions. In particular, fructose 1-phosphate can be biosynthesized from D-fructose through the action of the enzyme ketohexokinase. In addition, fructose 1-phosphate can be converted into dihydroxyacetone phosphate and glyceraldehyde; which is catalyzed by the enzyme fructose-bisphosphate aldolase a. Because fructokinase has a high Vmax fructose entering cells is quickly phosphorylated to fructose 1-phosphate. In humans, fructose 1-phosphate is involved in fructose intolerance, hereditary. Hypoglycemia results from inhibition of glycogenolysis and gluconeogenesis. It is generated mainly by hepatic fructokinase but is also generated in smaller amounts in the small intestinal mucosa and proximal epithelium of the renal tubule. Aldolase B converts it into glyceraldehyde and dihydroxyacetone phosphate (DHAP). Symptoms of hereditary fructose intolerance are apathy, drowsiness, sweatiness and tremulousness.
Structure
MOLSDFPDBSMILESInChI

MOL for #<Metabolite:0x000055b76df30528>

Not Available

3D MOL for #<Metabolite:0x000055b76df30528>

Not Available

3D SDF for #<Metabolite:0x000055b76df30528>

Not Available

3D-SDF for #<Metabolite:0x000055b76df30528>

Not Available

PDB for #<Metabolite:0x000055b76df30528>

Not Available

3D PDB for #<Metabolite:0x000055b76df30528>

Not Available

SMILES for #<Metabolite:0x000055b76df30528>

Not Available

INCHI for #<Metabolite:0x000055b76df30528>

Not Available
SynonymsNot Available
Chemical FormulaC6H13O9P
Average Molecular Weight260.1358
Monoisotopic Molecular Weight260.029718526
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry Number15978-08-2
SMILESNot Available
InChI Identifier
InChI=1S/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3,5-8,10-11H,1-2H2,(H2,12,13,14)/t3-,5-,6-/m1/s1
InChI KeyZKLLSNQJRLJIGT-UYFOZJQFSA-N