MiMeDB: Showing metabocard for Sedoheptulose 7-phosphate (MMDBc0033115)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:35:24 UTC

Update Date

2022-12-15 22:51:53 UTC

MiMeDB ID

MMDBc0033115

Metabolite Identification

Common Name

Sedoheptulose 7-phosphate

Description

true

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₇H₁₅O₁₀P

Average Molecular Weight

290.1618

Monoisotopic Molecular Weight

290.040283212

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

2646-35-7

SMILES

Not Available

InChI Identifier

InChI=1S/C7H15O10P/c8-1-3(9)5(11)7(13)6(12)4(10)2-17-18(14,15)16/h4-8,10-13H,1-2H2,(H2,14,15,16)/t4-,5-,6-,7+/m1/s1

InChI Key

JDTUMPKOJBQPKX-GBNDHIKLSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Cytoplasm

Biospecimen Locations

Blood
Cellular Cytoplasm
Fibroblasts
Placenta
Saliva

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Reference
Alzheimer's disease		This associated disease is originally imported from HMDB metabolite HMDB0001068 concentration id 93554	Association	Human Saliva	23857558	details
Frontotemporal dementia		This associated disease is originally imported from HMDB metabolite HMDB0001068 concentration id 93610	Association	Human Saliva	23857558	details
Transaldolase deficiency	Increased	This associated disease is originally imported from HMDB metabolite HMDB0001068 concentration id 17471	Association	Human Blood	12881455	details

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Fungi	Ascomycota	1	Human Feces	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	0.91	0.26	Adult (>18 years old)	Male	Alzheimer's disease	HMDB	23857558	details
Human	Detected and Quantified	0.84	0.13	Adult (>18 years old)	Male	Frontotemporal lobe dementia	HMDB	23857558	details
Human	Detected and Quantified	1.60	1.55	Adult (>18 years old)	Both	Lewy body disease	HMDB	23857558	details
Human	Detected and Quantified	5.19	0.84	Adult (>18 years old)	Both	Transaldolase deficiency	HMDB	12881455	details
Human	Detected and Quantified	74.9		Adult (>18 years old)	Both	Normal	HMDB	15882454	details
Human	Detected and Quantified	0.89	0.41	Adult (>18 years old)	Both	Normal	HMDB	12881455	details
Human	Detected and Quantified	1.15	0.44	Adult (>18 years old)	Female	Normal	HMDB	23857558	details
Human	Detected and Quantified	1.15	0.66	Children (1-13 years old)	Both	Normal	HMDB	12881455	details
Human	Detected and Quantified	0.299	0.236	Adult (>18 years old)	Not Specified	Normal	HMDB	Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles.	details
Human	Detected and Quantified	0.360	1.20	Adult (>18 years old)	Not Specified	Normal	HMDB	Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles.	details
Human Fibroblasts	Detected but not Quantified			Not Specified	Not Specified	Normal	HMDB	34986597	details
Human Placenta	Detected but not Quantified			Not Specified	Not Specified	Normal	HMDB	34986597	details

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Makarov SA, Kudriavtseva GV, Kolotilova AI: [Effect of prostaglandins F2 and F2 alpha on the pentosephosate pathway in human blood platelets]. Vopr Med Khim. 1983 Sep-Oct;29(5):27-32. [PubMed:6316661 ]
Thornalley PJ, Jahan I, Ng R: Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro. J Biochem. 2001 Apr;129(4):543-9. doi: 10.1093/oxfordjournals.jbchem.a002889. [PubMed:11275553 ]
Huck JH, Struys EA, Verhoeven NM, Jakobs C, van der Knaap MS: Profiling of pentose phosphate pathway intermediates in blood spots by tandem mass spectrometry: application to transaldolase deficiency. Clin Chem. 2003 Aug;49(8):1375-80. doi: 10.1373/49.8.1375. [PubMed:12881455 ]
Nakayama Y, Kinoshita A, Tomita M: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005 May 9;2:18. doi: 10.1186/1742-4682-2-18. [PubMed:15882454 ]
Wamelink MM, Struys EA, Huck JH, Roos B, van der Knaap MS, Jakobs C, Verhoeven NM: Quantification of sugar phosphate intermediates of the pentose phosphate pathway by LC-MS/MS: application to two new inherited defects of metabolism. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 25;823(1):18-25. doi: 10.1016/j.jchromb.2005.01.001. Epub 2005 Jan 23. [PubMed:16055050 ]
Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043. [PubMed:32033212 ]

Showing metabocard for Sedoheptulose 7-phosphate (MMDBc0033115)

MOL for #<Metabolite:0x000055b76e1bf118>

3D MOL for #<Metabolite:0x000055b76e1bf118>

3D SDF for #<Metabolite:0x000055b76e1bf118>

3D-SDF for #<Metabolite:0x000055b76e1bf118>

PDB for #<Metabolite:0x000055b76e1bf118>

3D PDB for #<Metabolite:0x000055b76e1bf118>

SMILES for #<Metabolite:0x000055b76e1bf118>

INCHI for #<Metabolite:0x000055b76e1bf118>

Structure for #<Metabolite:0x000055b76e1bf118>

3D Structure for #<Metabolite:0x000055b76e1bf118>