MiMeDB: Showing metabocard for PC(20:4(5Z,8Z,11Z,14Z)/22:0) (MMDBc0034046)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-19 05:13:55 UTC

Update Date

2022-12-15 22:52:07 UTC

MiMeDB ID

MMDBc0034046

Metabolite Identification

Common Name

PC(20:4(5Z,8Z,11Z,14Z)/22:0)

Description

PC(20:4(5Z,8Z,11Z,14Z)/22:0) is a phosphatidylcholine (PC or GPCho). It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, glycerophosphocholines can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. PC(20:4(5Z,8Z,11Z,14Z)/22:0), in particular, consists of one chain of arachidonic acid at the C-1 position and one chain of behenic acid at the C-2 position. The arachidonic acid moiety is derived from animal fats and eggs, while the behenic acid moiety is derived from groundnut oil. Phospholipids, are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling.‚Üµ‚ÜµWhile most phospholipids have a saturated fatty acid on C-1 and an unsaturated fatty acid on C-2 of the glycerol backbone, the fatty acid distribution at the C-1 and C-2 positions of glycerol within phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. PCs can be synthesized via three different routes. In one route, choline is activated first by phosphorylation and then by coupling to CDP prior to attachment to phosphatidic acid. PCs can also synthesized by the addition of choline to CDP-activated 1,2-diacylglycerol. A third route to PC synthesis involves the conversion of either PS or PE to PC.

Structure

MOL SDF PDB SMILES InChI


  Mrv0541 02251201422D          

 60 59  0  0  1  0            999 V2000
   16.6105   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.3250   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.0395   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.7539   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   19.4684   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   20.1829   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   20.8974   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   21.6118   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   22.3263   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.0408   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.7552   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   24.4697   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   25.1842   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   25.8987   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   26.6131   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   27.3276   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   28.0421   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   28.7565   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   29.4710   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.1855   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.8999   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144    9.1776    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   32.3289   10.4151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434   10.0026    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   33.7578   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   34.4723   10.0026    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   11.2401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   35.9012   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   36.6157   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   37.3302   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.0447   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.7591   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   11.2401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   40.1881   11.6526    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   40.1881   12.4776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   12.8901    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.7591   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.0447   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   37.3302   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   36.6157   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.9012   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   34.4723   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    9.1776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    8.7651    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    7.9401    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   34.5828    7.9401    0.0000 O   0  5  0  0  0  0  0  0  0  0  0  0
   32.9328    7.9401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    7.1151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    6.7026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    5.8776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   32.3289    5.4651    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
   31.9164    6.1796    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   32.7414    4.7506    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144    5.0526    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 25 24  1  6  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  2  0  0  0  0
 28 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 33 32  1  4  0  0  0
 33 34  2  0  0  0  0
 34 35  1  0  0  0  0
 36 35  1  4  0  0  0
 36 37  2  0  0  0  0
 37 38  1  0  0  0  0
 39 38  1  4  0  0  0
 39 40  2  0  0  0  0
 40 41  1  0  0  0  0
 42 41  1  4  0  0  0
 42 43  2  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 46 47  1  0  0  0  0
 47 48  1  0  0  0  0
 25 49  1  0  0  0  0
 49 50  1  0  0  0  0
 50 51  1  0  0  0  0
 51 52  1  0  0  0  0
 51 53  2  0  0  0  0
 51 54  1  0  0  0  0
 54 55  1  0  0  0  0
 55 56  1  0  0  0  0
 56 57  1  0  0  0  0
 57 58  1  0  0  0  0
 57 59  1  0  0  0  0
 57 60  1  0  0  0  0
M  CHG  2  52  -1  57   1
M  END


  Mrv0541 02251201422D          

 60 59  0  0  1  0            999 V2000
   16.6105   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   17.3250   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.0395   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   18.7539   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   19.4684   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   20.1829   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   20.8974   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   21.6118   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   22.3263   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.0408   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   23.7552   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   24.4697   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   25.1842   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   25.8987   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   26.6131   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   27.3276   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   28.0421   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   28.7565   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   29.4710   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.1855   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   30.8999   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144    9.1776    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   32.3289   10.4151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434   10.0026    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
   33.7578   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   34.4723   10.0026    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   11.2401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   35.9012   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   36.6157   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   37.3302   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.0447   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.7591   10.0026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   10.4151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   11.2401    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   40.1881   11.6526    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   40.1881   12.4776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   12.8901    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   39.4736   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.7591   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   38.0447   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   37.3302   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   36.6157   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.9012   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   35.1868   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   34.4723   14.1276    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578   13.7151    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    9.1776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    8.7651    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    7.9401    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   34.5828    7.9401    0.0000 O   0  5  0  0  0  0  0  0  0  0  0  0
   32.9328    7.9401    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.7578    7.1151    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    6.7026    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   33.0434    5.8776    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   32.3289    5.4651    0.0000 N   0  3  0  0  0  0  0  0  0  0  0  0
   31.9164    6.1796    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   32.7414    4.7506    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   31.6144    5.0526    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  2  3  1  0  0  0  0
  3  4  1  0  0  0  0
  4  5  1  0  0  0  0
  5  6  1  0  0  0  0
  6  7  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
  9 10  1  0  0  0  0
 10 11  1  0  0  0  0
 11 12  1  0  0  0  0
 12 13  1  0  0  0  0
 13 14  1  0  0  0  0
 14 15  1  0  0  0  0
 15 16  1  0  0  0  0
 16 17  1  0  0  0  0
 17 18  1  0  0  0  0
 18 19  1  0  0  0  0
 19 20  1  0  0  0  0
 20 21  1  0  0  0  0
 21 22  1  0  0  0  0
 22 23  2  0  0  0  0
 22 24  1  0  0  0  0
 25 24  1  6  0  0  0
 25 26  1  0  0  0  0
 26 27  1  0  0  0  0
 27 28  1  0  0  0  0
 28 29  2  0  0  0  0
 28 30  1  0  0  0  0
 30 31  1  0  0  0  0
 31 32  1  0  0  0  0
 33 32  1  4  0  0  0
 33 34  2  0  0  0  0
 34 35  1  0  0  0  0
 36 35  1  4  0  0  0
 36 37  2  0  0  0  0
 37 38  1  0  0  0  0
 39 38  1  4  0  0  0
 39 40  2  0  0  0  0
 40 41  1  0  0  0  0
 42 41  1  4  0  0  0
 42 43  2  0  0  0  0
 43 44  1  0  0  0  0
 44 45  1  0  0  0  0
 45 46  1  0  0  0  0
 46 47  1  0  0  0  0
 47 48  1  0  0  0  0
 25 49  1  0  0  0  0
 49 50  1  0  0  0  0
 50 51  1  0  0  0  0
 51 52  1  0  0  0  0
 51 53  2  0  0  0  0
 51 54  1  0  0  0  0
 54 55  1  0  0  0  0
 55 56  1  0  0  0  0
 56 57  1  0  0  0  0
 57 58  1  0  0  0  0
 57 59  1  0  0  0  0
 57 60  1  0  0  0  0
M  CHG  2  52  -1  57   1
M  END
> <DATABASE_ID>
MMDBc0034046

> <DATABASE_NAME>
MIME

> <SMILES>
CCCCCCCCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCC=CCC=CCC=CCC=CCCCCC)COP([O-])(=O)OCC[N+](C)(C)C

> <INCHI_IDENTIFIER>
InChI=1S/C50H92NO8P/c1-6-8-10-12-14-16-18-20-22-24-25-27-29-31-33-35-37-39-41-43-50(53)59-48(47-58-60(54,55)57-45-44-51(3,4)5)46-56-49(52)42-40-38-36-34-32-30-28-26-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,28,30,34,36,48H,6-14,16,18-20,22,24-27,29,31-33,35,37-47H2,1-5H3/t48-/m1/s1

> <INCHI_KEY>
CVECNRQDBOYLEX-QSCHNALKSA-N

> <FORMULA>
C50H92NO8P

> <MOLECULAR_WEIGHT>
866.2411

> <EXACT_MASS>
865.656055437

> <JCHEM_ACCEPTOR_COUNT>
4

> <JCHEM_AVERAGE_POLARIZABILITY>
107.35581998904377

> <JCHEM_BIOAVAILABILITY>
0

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2-{[(2R)-2-(docosanoyloxy)-3-(icosa-5,8,11,14-tetraenoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium

> <ALOGPS_LOGP>
6.63

> <JCHEM_LOGP>
11.111796402528253

> <ALOGPS_LOGS>
-7.53

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.8550572064467632

> <JCHEM_PKA_STRONGEST_BASIC>
-6.744219009617095

> <JCHEM_POLAR_SURFACE_AREA>
111.19000000000001

> <JCHEM_REFRACTIVITY>
266.34150000000005

> <JCHEM_ROTATABLE_BOND_COUNT>
46

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
2.69e-05 g/l

> <JCHEM_TRADITIONAL_IUPAC>
(2-{[(2R)-2-(docosanoyloxy)-3-(icosa-5,8,11,14-tetraenoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium

> <JCHEM_VEBER_RULE>
0

$$$$

HEADER    PROTEIN                                 25-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   25-FEB-12         0                                  
HETATM    1  C   UNK     0      31.006  19.442   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0      32.340  18.672   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0      33.674  19.442   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      35.007  18.672   0.000  0.00  0.00           C+0
HETATM    5  C   UNK     0      36.341  19.442   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0      37.675  18.672   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0      39.008  19.442   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0      40.342  18.672   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0      41.676  19.442   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0      43.009  18.672   0.000  0.00  0.00           C+0
HETATM   11  C   UNK     0      44.343  19.442   0.000  0.00  0.00           C+0
HETATM   12  C   UNK     0      45.677  18.672   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0      47.011  19.442   0.000  0.00  0.00           C+0
HETATM   14  C   UNK     0      48.344  18.672   0.000  0.00  0.00           C+0
HETATM   15  C   UNK     0      49.678  19.442   0.000  0.00  0.00           C+0
HETATM   16  C   UNK     0      51.012  18.672   0.000  0.00  0.00           C+0
HETATM   17  C   UNK     0      52.345  19.442   0.000  0.00  0.00           C+0
HETATM   18  C   UNK     0      53.679  18.672   0.000  0.00  0.00           C+0
HETATM   19  C   UNK     0      55.013  19.442   0.000  0.00  0.00           C+0
HETATM   20  C   UNK     0      56.346  18.672   0.000  0.00  0.00           C+0
HETATM   21  C   UNK     0      57.680  19.442   0.000  0.00  0.00           C+0
HETATM   22  C   UNK     0      59.014  18.672   0.000  0.00  0.00           C+0
HETATM   23  O   UNK     0      59.014  17.132   0.000  0.00  0.00           O+0
HETATM   24  O   UNK     0      60.347  19.442   0.000  0.00  0.00           O+0
HETATM   25  C   UNK     0      61.681  18.672   0.000  0.00  0.00           C+0
HETATM   26  C   UNK     0      63.015  19.442   0.000  0.00  0.00           C+0
HETATM   27  O   UNK     0      64.348  18.672   0.000  0.00  0.00           O+0
HETATM   28  C   UNK     0      65.682  19.442   0.000  0.00  0.00           C+0
HETATM   29  O   UNK     0      65.682  20.982   0.000  0.00  0.00           O+0
HETATM   30  C   UNK     0      67.016  18.672   0.000  0.00  0.00           C+0
HETATM   31  C   UNK     0      68.349  19.442   0.000  0.00  0.00           C+0
HETATM   32  C   UNK     0      69.683  18.672   0.000  0.00  0.00           C+0
HETATM   33  C   UNK     0      71.017  19.442   0.000  0.00  0.00           C+0
HETATM   34  C   UNK     0      72.350  18.672   0.000  0.00  0.00           C+0
HETATM   35  C   UNK     0      73.684  19.442   0.000  0.00  0.00           C+0
HETATM   36  C   UNK     0      73.684  20.982   0.000  0.00  0.00           C+0
HETATM   37  C   UNK     0      75.018  21.752   0.000  0.00  0.00           C+0
HETATM   38  C   UNK     0      75.018  23.292   0.000  0.00  0.00           C+0
HETATM   39  C   UNK     0      73.684  24.062   0.000  0.00  0.00           C+0
HETATM   40  C   UNK     0      73.684  25.602   0.000  0.00  0.00           C+0
HETATM   41  C   UNK     0      72.350  26.372   0.000  0.00  0.00           C+0
HETATM   42  C   UNK     0      71.017  25.602   0.000  0.00  0.00           C+0
HETATM   43  C   UNK     0      69.683  26.372   0.000  0.00  0.00           C+0
HETATM   44  C   UNK     0      68.349  25.602   0.000  0.00  0.00           C+0
HETATM   45  C   UNK     0      67.016  26.372   0.000  0.00  0.00           C+0
HETATM   46  C   UNK     0      65.682  25.602   0.000  0.00  0.00           C+0
HETATM   47  C   UNK     0      64.348  26.372   0.000  0.00  0.00           C+0
HETATM   48  C   UNK     0      63.015  25.602   0.000  0.00  0.00           C+0
HETATM   49  C   UNK     0      61.681  17.132   0.000  0.00  0.00           C+0
HETATM   50  O   UNK     0      63.015  16.362   0.000  0.00  0.00           O+0
HETATM   51  P   UNK     0      63.015  14.822   0.000  0.00  0.00           P+0
HETATM   52  O   UNK     0      64.555  14.822   0.000  0.00  0.00           O-1
HETATM   53  O   UNK     0      61.475  14.822   0.000  0.00  0.00           O+0
HETATM   54  O   UNK     0      63.015  13.282   0.000  0.00  0.00           O+0
HETATM   55  C   UNK     0      61.681  12.512   0.000  0.00  0.00           C+0
HETATM   56  C   UNK     0      61.681  10.972   0.000  0.00  0.00           C+0
HETATM   57  N   UNK     0      60.347  10.202   0.000  0.00  0.00           N+1
HETATM   58  C   UNK     0      59.577  11.535   0.000  0.00  0.00           C+0
HETATM   59  C   UNK     0      61.117   8.868   0.000  0.00  0.00           C+0
HETATM   60  C   UNK     0      59.014   9.432   0.000  0.00  0.00           C+0
CONECT    1    2                                                            
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3    5                                                       
CONECT    5    4    6                                                       
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9   11                                                       
CONECT   11   10   12                                                       
CONECT   12   11   13                                                       
CONECT   13   12   14                                                       
CONECT   14   13   15                                                       
CONECT   15   14   16                                                       
CONECT   16   15   17                                                       
CONECT   17   16   18                                                       
CONECT   18   17   19                                                       
CONECT   19   18   20                                                       
CONECT   20   19   21                                                       
CONECT   21   20   22                                                       
CONECT   22   21   23   24                                                  
CONECT   23   22                                                            
CONECT   24   22   25                                                       
CONECT   25   24   26   49                                                  
CONECT   26   25   27                                                       
CONECT   27   26   28                                                       
CONECT   28   27   29   30                                                  
CONECT   29   28                                                            
CONECT   30   28   31                                                       
CONECT   31   30   32                                                       
CONECT   32   31   33                                                       
CONECT   33   32   34                                                       
CONECT   34   33   35                                                       
CONECT   35   34   36                                                       
CONECT   36   35   37                                                       
CONECT   37   36   38                                                       
CONECT   38   37   39                                                       
CONECT   39   38   40                                                       
CONECT   40   39   41                                                       
CONECT   41   40   42                                                       
CONECT   42   41   43                                                       
CONECT   43   42   44                                                       
CONECT   44   43   45                                                       
CONECT   45   44   46                                                       
CONECT   46   45   47                                                       
CONECT   47   46   48                                                       
CONECT   48   47                                                            
CONECT   49   25   50                                                       
CONECT   50   49   51                                                       
CONECT   51   50   52   53   54                                             
CONECT   52   51                                                            
CONECT   53   51                                                            
CONECT   54   51   55                                                       
CONECT   55   54   56                                                       
CONECT   56   55   57                                                       
CONECT   57   56   58   59   60                                             
CONECT   58   57                                                            
CONECT   59   57                                                            
CONECT   60   57                                                            
MASTER        0    0    0    0    0    0    0    0   60    0  118    0
END

Synonyms

Not Available

Chemical Formula

C₅₀H₉₂NO₈P

Average Molecular Weight

866.2411

Monoisotopic Molecular Weight

865.656055437

IUPAC Name

(2-{[(2R)-2-(docosanoyloxy)-3-(icosa-5,8,11,14-tetraenoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium

Traditional Name

(2-{[(2R)-2-(docosanoyloxy)-3-(icosa-5,8,11,14-tetraenoyloxy)propyl phosphonato]oxy}ethyl)trimethylazanium

CAS Registry Number

Not Available

SMILES

CCCCCCCCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCCC=CCC=CCC=CCC=CCCCCC)COP([O-])(=O)OCC[N+](C)(C)C

InChI Identifier

InChI=1S/C50H92NO8P/c1-6-8-10-12-14-16-18-20-22-24-25-27-29-31-33-35-37-39-41-43-50(53)59-48(47-58-60(54,55)57-45-44-51(3,4)5)46-56-49(52)42-40-38-36-34-32-30-28-26-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,28,30,34,36,48H,6-14,16,18-20,22,24-27,29,31-33,35,37-47H2,1-5H3/t48-/m1/s1

InChI Key

CVECNRQDBOYLEX-QSCHNALKSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phosphatidylcholines. These are glycerophosphocholines in which the two free -OH are attached to one fatty acid each through an ester linkage.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Glycerophospholipids

Sub Class

Glycerophosphocholines

Direct Parent

Phosphatidylcholines

Alternative Parents

Substituents

Diacylglycero-3-phosphocholine
Phosphocholine
Fatty acid ester
Dialkyl phosphate
Dicarboxylic acid or derivatives
Organic phosphoric acid derivative
Phosphoric acid ester
Alkyl phosphate
Fatty acyl
Quaternary ammonium salt
Tetraalkylammonium salt
Carboxylic acid ester
Carboxylic acid derivative
Organic oxygen compound
Organic nitrogen compound
Carbonyl group
Organooxygen compound
Organonitrogen compound
Organic oxide
Organopnictogen compound
Amine
Organic salt
Hydrocarbon derivative
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Property	Value	Source
Water Solubility	2.7e-05 g/L	ALOGPS
logP	6.63	ALOGPS
logP	11.11	ChemAxon
logS	-7.5	ALOGPS
pKa (Strongest Acidic)	1.86	ChemAxon
pKa (Strongest Basic)	-6.7	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	4	ChemAxon
Hydrogen Donor Count	0	ChemAxon
Polar Surface Area	111.19 Å²	ChemAxon
Rotatable Bond Count	46	ChemAxon
Refractivity	266.34 m³·mol⁻¹	ChemAxon
Polarizability	107.36 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Not Available

Biological Properties

Cellular Locations

Extracellular
Membrane

Biospecimen Locations

All Tissues
Blood
Feces
Saliva
Urine

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Proteins

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Not Available

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Related Health Condition	Evidence Type	Measured in Matrix	Data Source	Reference
Obesity		This associated disease is originally imported from HMDB metabolite HMDB0008446 concentration id 140662	Association	Human Blood		Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children	details
Obesity		This associated disease is originally imported from HMDB metabolite HMDB0008446 concentration id 140663	Association	Human Blood		Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children	details

Microbial Sources

Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Fungi	Ascomycota	1	Human Feces	Unknown

Exposure Sources

Source Type	Source Sub-type	Species	Data Source	Reference	Details
Animal	Milk	Bos taurus	FooDB	31437929	details
Animal	Milk	Bos taurus	FooDB	31437929	details

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Age	Sex	Health Condition	Data Source	Reference
Human	Detected and Quantified	0.2922	0.08			Adult (>18 years old)	Female	Pregnancy	HMDB	24704061	details
Human	Detected and Quantified	0.0008		0.0003	0.0025	Adult (>18 years old)	Both	Normal	HMDB	24023812	details
Human	Detected and Quantified	0.02	0.01			Adult (>18 years old)	Both	Normal	HMDB	27624970	details
Human	Detected and Quantified	0.03	0.01			Adult (>18 years old)	Both	Normal	HMDB	27624970	details
Human	Detected and Quantified	0.18	0.04			Adult (>18 years old)	Both	Normal	HMDB	28278231	details
Human	Detected and Quantified	0.2		0.17	0.23	Infant (0-1 year old)		Normal	HMDB	25754623	details
Human	Detected and Quantified	0.24		0.2	0.32	Newborn (0-30 days old)		Normal	HMDB	25754623	details
Human	Detected and Quantified	0.172	0.059			Children (1-13 years old)	Both	Obesity	HMDB	Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children	details
Human	Detected and Quantified	0.185	0.060			Children (1-13 years old)	Both	Obesity	HMDB	Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children	details
Human	Detected and Quantified	0.007	0.001			Adult (>18 years old)	Both	Normal	HMDB	Zerihun T. Dame, Farid Aziat, Rupasri Mandal, Ram Krishnamurthy, Souhaila Bouatra, Shima Borzouie, An Chi Guo, Tanvir Sajed, Lu Deng, Hong Lin, Philip Liu, Edison Dong, David S. Wishart "The human saliva metabolome" Metabolomics (2015) DOI 10.1007/s11306-015-0840-5	details
Human All Tissues	Detected but not Quantified					Not Specified	Not Specified	Normal	HMDB	34986597	details

External Links

HMDB ID

Not Available

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB025636

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

General References

Ramirez-Gaona M, Marcu A, Pon A, Guo AC, Sajed T, Wishart NA, Karu N, Djoumbou Feunang Y, Arndt D, Wishart DS: YMDB 2.0: a significantly expanded version of the yeast metabolome database. Nucleic Acids Res. 2017 Jan 4;45(D1):D440-D445. doi: 10.1093/nar/gkw1058. Epub 2016 Nov 28. [PubMed:27899612 ]

Showing metabocard for PC(20:4(5Z,8Z,11Z,14Z)/22:0) (MMDBc0034046)

MOL for #<Metabolite:0x000055b76bbe98f8>

3D MOL for #<Metabolite:0x000055b76bbe98f8>

3D SDF for #<Metabolite:0x000055b76bbe98f8>

3D-SDF for #<Metabolite:0x000055b76bbe98f8>

PDB for #<Metabolite:0x000055b76bbe98f8>

3D PDB for #<Metabolite:0x000055b76bbe98f8>

SMILES for #<Metabolite:0x000055b76bbe98f8>

INCHI for #<Metabolite:0x000055b76bbe98f8>

Structure for #<Metabolite:0x000055b76bbe98f8>

3D Structure for #<Metabolite:0x000055b76bbe98f8>