Showing metabocard for PG(14:0/20:0) (MMDBc0046528)
Record Information
Version
1.0
Status
Detected and Quantified
Creation Date
2021-11-19 14:41:05 UTC
Update Date
2022-09-01 01:32:54 UTC
MiMeDB ID
MMDBc0046528
Metabolite Identification
Common Name
PG(14:0/20:0)
Description
PG(14:0/20:0) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(14:0/20:0), in particular, consists of one tetradecanoyl chain to the C-1 atom, and one eicosanoyl to the C-2 atom. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.
