Showing metabocard for PG(22:1(11Z)/22:1(11Z)) (MMDBc0046930)
Record Information
Version
1.0
Status
Detected and Quantified
Creation Date
2021-11-19 15:00:33 UTC
Update Date
2022-09-01 01:39:36 UTC
MiMeDB ID
MMDBc0046930
Metabolite Identification
Common Name
PG(22:1(11Z)/22:1(11Z))
Description
PG(22:1(11Z)/22:1(11Z)) is a phosphatidylglycerol. Phosphatidylglycerols consist of a glycerol 3-phosphate backbone esterified to either saturated or unsaturated fatty acids on carbons 1 and 2. As is the case with diacylglycerols, phosphatidylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PG(22:1(11Z)/22:1(11Z)), in particular, consists of two 11Z-docosenoyl chains at positions C-1 and C-2. In E. coli glycerophospholipid metabolism, phosphatidylglycerol is formed from phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by a sequence of enzymatic reactions that proceeds via two intermediates, cytidine diphosphate diacylglycerol (CDP-diacylglycerol) and phosphatidylglycerophosphate (PGP, a phosphorylated phosphatidylglycerol). Phosphatidylglycerols, along with CDP-diacylglycerol, also serve as precursor molecules for the synthesis of cardiolipin, a phospholipid found in membranes.
