MiMeDB: Showing metabocard for Dihydroceramide (MMDBc0047795)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-19 15:43:00 UTC

Update Date

2022-09-01 01:59:06 UTC

Metabolite ID

MMDBc0047795

Metabolite Identification

Common Name

Dihydroceramide

Description

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₁₉H₃₉NO₃

Average Mass

329.5179

Monoisotopic Mass

329.292994119

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C19H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(23)18(16-21)20-17-22/h17-19,21,23H,2-16H2,1H3,(H,20,22)/t18-,19+/m0/s1

InChI Key

XSDVOEIEBUGRQX-RBUKOAKNSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Chromatographic Retention Times and Retention Indices

Retention Times

Not Available

Retention Indices

Not Available

Biological Properties

Cellular Locations

Extracellular
Membrane

Biospecimen Locations

Feces

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species
MMDBp0191985	Galactocerebrosidase	Enzyme	P54803	Homo_sapiens
MMDBp0192100	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	Unknown	Q8N5D6	Homo_sapiens
MMDBp0192203	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase	Enzyme	Q9Y2B2	Homo_sapiens
MMDBp0192391	Phosphatidylcholine:ceramide cholinephosphotransferase 2	Enzyme	Q8NHU3	Homo_sapiens
MMDBp0192395	Phosphatidylcholine:ceramide cholinephosphotransferase 1	Enzyme	Q86VZ5	Homo_sapiens
MMDBp0192396	Sphingomyelin phosphodiesterase	Enzyme	P17405	Homo_sapiens
MMDBp0192465	Ceramide glucosyltransferase	Enzyme	Q16739	Homo_sapiens
MMDBp0192558	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q	Enzyme	Q9BRB3	Homo_sapiens
MMDBp0192559	Phosphatidylinositol N-acetylglucosaminyltransferase subunit A	Enzyme	P37287	Homo_sapiens
MMDBp0192560	Phosphatidylinositol N-acetylglucosaminyltransferase subunit H	Enzyme	Q14442	Homo_sapiens
MMDBp0192561	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P	Enzyme	P57054	Homo_sapiens
MMDBp0192562	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C	Enzyme	Q92535	Homo_sapiens
MMDBp0192661	Sphingosine-1-phosphate lyase 1	Enzyme	O95470	Homo_sapiens
MMDBp0192688	Sphingosine kinase 1	Unknown	Q9NYA1	Homo_sapiens
MMDBp0192690	Acid ceramidase	Enzyme	Q13510	Homo_sapiens
MMDBp0192695	Ectonucleotide pyrophosphatase/phosphodiesterase family member 7	Unknown	Q6UWV6	Homo_sapiens
MMDBp0192696	Sphingomyelin phosphodiesterase 2	Unknown	O60906	Homo_sapiens
MMDBp0192707	2-hydroxyacylsphingosine 1-beta-galactosyltransferase	Enzyme	Q16880	Homo_sapiens
MMDBp0192889	Collagen type IV alpha-3-binding protein	Enzyme	Q9Y5P4	Homo_sapiens
MMDBp0192976	Ceramide kinase	Unknown	Q8TCT0	Homo_sapiens
MMDBp0193223	Ganglioside GM2 activator	Enzyme	P17900	Homo_sapiens
MMDBp0193267	Glucosylceramidase	Enzyme	P04062	Homo_sapiens
MMDBp0193531	T-cell surface glycoprotein CD1e, membrane-associated	Enzyme	P15812	Homo_sapiens
MMDBp0193636	Epididymal secretory protein E1	Enzyme	P61916	Homo_sapiens
MMDBp0193670	Ceramide synthase 1	Enzyme	P27544	Homo_sapiens
MMDBp0193673	Antigen-presenting glycoprotein CD1d	Enzyme	P15813	Homo_sapiens
MMDBp0193742	GPI mannosyltransferase 1	Enzyme	Q9H3S5	Homo_sapiens
MMDBp0193755	Phosphatidylinositol-glycan biosynthesis class W protein	Enzyme	Q7Z7B1	Homo_sapiens
MMDBp0193805	Phosphatidylinositol-glycan biosynthesis class X protein	Enzyme	Q8TBF5	Homo_sapiens
MMDBp0193806	GPI mannosyltransferase 4	Enzyme	Q86VD9	Homo_sapiens
MMDBp0194033	Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase	Enzyme	Q9BYG0	Homo_sapiens
MMDBp0194037	Sphingomyelin phosphodiesterase 3	Unknown	Q9NY59	Homo_sapiens
MMDBp0194044	Beta-1,3-galactosyltransferase 5	Enzyme	Q9Y2C3	Homo_sapiens
MMDBp0194119	GPI mannosyltransferase 3	Enzyme	Q92521	Homo_sapiens
MMDBp0194120	Phosphatidylinositol-glycan biosynthesis class F protein	Enzyme	Q07326	Homo_sapiens
MMDBp0194121	GPI ethanolamine phosphate transferase 2	Enzyme	Q5H8A4	Homo_sapiens
MMDBp0194122	GPI ethanolamine phosphate transferase 1	Enzyme	O95427	Homo_sapiens
MMDBp0194123	GPI ethanolamine phosphate transferase 3	Enzyme	Q8TEQ8	Homo_sapiens
MMDBp0194124	GPI transamidase component PIG-S	Enzyme	Q96S52	Homo_sapiens
MMDBp0194125	GPI transamidase component PIG-T	Enzyme	Q969N2	Homo_sapiens
MMDBp0194126	Phosphatidylinositol glycan anchor biosynthesis class U protein	Enzyme	Q9H490	Homo_sapiens
MMDBp0194127	GPI mannosyltransferase 2	Enzyme	Q9NUD9	Homo_sapiens
MMDBp0194128	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y	Enzyme	Q3MUY2	Homo_sapiens
MMDBp0194133	Pleckstrin homology domain-containing family A member 8	Unknown	Q96JA3	Homo_sapiens
MMDBp0194188	Alkaline ceramidase 3	Enzyme	Q9NUN7	Homo_sapiens
MMDBp0194189	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2	Enzyme	Q6QHC5	Homo_sapiens
MMDBp0195538	Sphingomyelin phosphodiesterase 4	Unknown	Q9NXE4	Homo_sapiens
MMDBp0195879	Putative neutral ceramidase C	Enzyme	P0C7U2	Homo_sapiens
MMDBp0195880	Alkaline ceramidase 2	Enzyme	Q5QJU3	Homo_sapiens
MMDBp0195881	Neutral ceramidase	Enzyme	Q9NR71	Homo_sapiens
MMDBp0195885	Non-lysosomal glucosylceramidase	Enzyme	Q9HCG7	Homo_sapiens
MMDBp0196227	Alkaline ceramidase 1	Enzyme	Q8TDN7	Homo_sapiens
MMDBp0196313	Killer cell lectin-like receptor subfamily B member 1	Unknown	Q12918	Homo_sapiens
MMDBp0196460	Protein FAN	Enzyme	Q92636	Homo_sapiens
MMDBp0196494	Ceramide synthase 5	Unknown	Q8N5B7	Homo_sapiens
MMDBp0196495	ATP-binding cassette sub-family A member 7	Unknown	Q8IZY2	Homo_sapiens
MMDBp0196528	GPI-anchor transamidase	Enzyme	Q92643	Homo_sapiens
MMDBp0196556	Glycosylphosphatidylinositol anchor attachment 1 protein	Unknown	O43292	Homo_sapiens
MMDBp0196557	Protein PLEKHA9	Unknown	O95397	Homo_sapiens
MMDBp0196558	Glycolipid transfer protein domain-containing protein 2	Unknown	A6NH11	Homo_sapiens
MMDBp0196559	Putative uncharacterized protein PLEKHA8	Unknown	B5MDU3	Homo_sapiens
MMDBp0196560	T-cell surface glycoprotein CD1a	Unknown	P06126	Homo_sapiens
MMDBp0196561	Glycolipid transfer protein domain-containing protein 1	Unknown	Q5TA50	Homo_sapiens
MMDBp0196562	T-cell surface glycoprotein CD1c	Unknown	P29017	Homo_sapiens
MMDBp0196563	Lipopolysaccharide-binding protein	Unknown	P18428	Homo_sapiens
MMDBp0196564	Putative uncharacterized protein DKFZp434L0435	Unknown	Q9UFH6	Homo_sapiens
MMDBp0196565	T-cell surface glycoprotein CD1b	Unknown	P29016	Homo_sapiens
MMDBp0196566	Glycolipid transfer protein	Unknown	Q9NZD2	Homo_sapiens

Human Pathways

Pathways

Name	SMPDB/PathBank

Microbial Pathways

Pathways

Not Available

Metabolic Reactions

Reactions

This table shows at most 20 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	1	Human feces	Unknown

Exposure Sources

Other Exposures

Source Type	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Mean	Std	Min	Max	Units	Age	Sex	Health Condition	Data Source	Reference
Human Feces	Detected but not Quantified									HMDB

External Links

Not Available

General References

Cadena DL, Kurten RC, Gill GN: The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis. Biochemistry. 1997 Jun 10;36(23):6960-7. doi: 10.1021/bi970091l. [PubMed:9188692 ]
Noronha A, Modamio J, Jarosz Y, Guerard E, Sompairac N, Preciat G, Danielsdottir AD, Krecke M, Merten D, Haraldsdottir HS, Heinken A, Heirendt L, Magnusdottir S, Ravcheev DA, Sahoo S, Gawron P, Friscioni L, Garcia B, Prendergast M, Puente A, Rodrigues M, Roy A, Rouquaya M, Wiltgen L, Zagare A, John E, Krueger M, Kuperstein I, Zinovyev A, Schneider R, Fleming RMT, Thiele I: The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992. [PubMed:30371894 ]
Wishart DS, Li C, Marcu A, Badran H, Pon A, Budinski Z, Patron J, Lipton D, Cao X, Oler E, Li K, Paccoud M, Hong C, Guo AC, Chan C, Wei W, Ramirez-Gaona M: PathBank: a comprehensive pathway database for model organisms. Nucleic Acids Res. 2020 Jan 8;48(D1):D470-D478. doi: 10.1093/nar/gkz861. [PubMed:31602464 ]

Showing metabocard for Dihydroceramide (MMDBc0047795)

MOL for #<Metabolite:0x00007f12196cbe98>

3D MOL for #<Metabolite:0x00007f12196cbe98>

3D SDF for #<Metabolite:0x00007f12196cbe98>

3D-SDF for #<Metabolite:0x00007f12196cbe98>

PDB for #<Metabolite:0x00007f12196cbe98>

3D PDB for #<Metabolite:0x00007f12196cbe98>

SMILES for #<Metabolite:0x00007f12196cbe98>

INCHI for #<Metabolite:0x00007f12196cbe98>

Structure for #<Metabolite:0x00007f12196cbe98>

3D Structure for #<Metabolite:0x00007f12196cbe98>