| Description | CDP-DG(18:2(9Z,12Z)/18:2(9Z,12Z)) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. CDP-DG(18:2(9Z,12Z)/18:2(9Z,12Z)), in particular, consists of one 9Z,12Z-octadecadienoyl chain at the C-1 position and one 9Z,12Z-octadecadienoyl chain at the C-2 position. In E. coli glycerophospholipid metabolism, the biosynthesis of CDP-diacylglycerol (CDP-DG) involves condensation of phosphatidic acid (PA) and cytidine triphosphate, with elimination of pyrophosphate, catalysed by the enzyme CDP-diacylglycerol synthase. The resulting CDP-diacylglycerol can be utilized immediately for the synthesis of phosphatidylglycerol (PG), and thence cardiolipin (CL), and of phosphatidylinositol (PI). CDP-DG(18:2(9Z,12Z)/18:2(9Z,12Z)) is also a substrate of CDP-diacylglycerol pyrophosphatase. It is involved in CDP-diacylglycerol degradation pathway. |
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| Synonyms | | Value | Source |
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| 1-Linoleoyl-2-linoleoyl-sn-glycero-3-CDP | HMDB | | 1-Linoleoyl-2-linoleoyl-sn-glycero-3-cytidine-5'-diphosphate | HMDB | | CDP-DG(18:2/18:2) | HMDB | | CDP-DG(18:2N6/18:2N6) | HMDB | | CDP-DG(18:2W6/18:2W6) | HMDB | | CDP-DG(36:4) | HMDB | | CDP-Diacylglycerol(18:2(9Z,12Z)/18:2(9Z,12Z)) | HMDB | | CDP-Diacylglycerol(18:2/18:2) | HMDB | | CDP-Diacylglycerol(18:2N6/18:2N6) | HMDB | | CDP-Diacylglycerol(18:2W6/18:2W6) | HMDB | | CDP-Diacylglycerol(36:4) | HMDB | | ({[(2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propoxy](hydroxy)phosphoryl}oxy)({[(2R,3R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphinate | HMDB | | 1-linoleoyl-2-linoleoyl-sn-glycero-3-CDP | SMPDB, HMDB | | 1-linoleoyl-2-linoleoyl-sn-glycero-3-cytidine-5'-diphosphate | SMPDB, HMDB | | CDP-DG(18:2/18:2) | SMPDB, HMDB | | CDP-DG(18:2n6/18:2n6) | SMPDB, HMDB | | CDP-DG(18:2w6/18:2w6) | SMPDB, HMDB | | CDP-DG(36:4) | SMPDB, HMDB | | CDP-diacylglycerol(18:2(9Z,12Z)/18:2(9Z,12Z)) | SMPDB, HMDB | | CDP-diacylglycerol(18:2/18:2) | SMPDB, HMDB | | CDP-diacylglycerol(18:2n6/18:2n6) | SMPDB, HMDB | | CDP-diacylglycerol(18:2w6/18:2w6) | SMPDB, HMDB | | CDP-DG(18:2(9Z,12Z)/18:2(9Z,12Z)) | SMPDB |
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| InChI Identifier | InChI=1S/C48H81N3O15P2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56/h11-14,17-20,35-36,40-41,45-47,54-55H,3-10,15-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56)/b13-11-,14-12-,19-17-,20-18-/t40-,41-,45+,46?,47-/m1/s1 |
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