| Description | CDP-DG(22:1(11Z)/24:1(9Z)) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. CDP-DG(22:1(11Z)/24:1(9Z)), in particular, consists of one 11Z-docosenoyl chain at the C-1 position and one 9Z-tetracosenoyl chain at the C-2 position. In E. coli glycerophospholipid metabolism, the biosynthesis of CDP-diacylglycerol (CDP-DG) involves condensation of phosphatidic acid (PA) and cytidine triphosphate, with elimination of pyrophosphate, catalysed by the enzyme CDP-diacylglycerol synthase. The resulting CDP-diacylglycerol can be utilized immediately for the synthesis of phosphatidylglycerol (PG), and thence cardiolipin (CL), and of phosphatidylinositol (PI). CDP-DG(22:1(11Z)/24:1(9Z)) is also a substrate of CDP-diacylglycerol pyrophosphatase. It is involved in CDP-diacylglycerol degradation pathway. |
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| InChI Identifier | InChI=1S/C58H105N3O15P2/c1-3-5-7-9-11-13-15-17-19-21-23-24-26-28-30-32-34-36-38-40-42-44-54(63)74-50(47-71-53(62)43-41-39-37-35-33-31-29-27-25-22-20-18-16-14-12-10-8-6-4-2)48-72-77(67,68)76-78(69,70)73-49-51-55(64)56(65)57(75-51)61-46-45-52(59)60-58(61)66/h22,25,28,30,45-46,50-51,55-57,64-65H,3-21,23-24,26-27,29,31-44,47-49H2,1-2H3,(H,67,68)(H,69,70)(H2,59,60,66)/b25-22-,30-28-/t50-,51-,55-,56-,57-/m1/s1 |
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