| Description | CDP-DG(22:1(11Z)/28:1(9Z)) is a cytidine diphosphate diacylglycerol or CDP-diacylglycerol. It is a glycerophospholipid in which a cytidine diphosphate moiety occupies a glycerol substitution site. As is the case with diacylglycerols, CDP-diacylglycerols can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. CDP-DG(22:1(11Z)/28:1(9Z)), in particular, consists of one 11Z-docosenoyl chain at the C-1 position and one 9Z-octacosanoyl chain at the C-2 position. In E. coli glycerophospholipid metabolism, the biosynthesis of CDP-diacylglycerol (CDP-DG) involves condensation of phosphatidic acid (PA) and cytidine triphosphate, with elimination of pyrophosphate, catalysed by the enzyme CDP-diacylglycerol synthase. The resulting CDP-diacylglycerol can be utilized immediately for the synthesis of phosphatidylglycerol (PG), and thence cardiolipin (CL), and of phosphatidylinositol (PI). CDP-DG(22:1(11Z)/28:1(9Z)) is also a substrate of CDP-diacylglycerol pyrophosphatase. It is involved in CDP-diacylglycerol degradation pathway. |
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| InChI Identifier | InChI=1S/C62H113N3O15P2/c1-3-5-7-9-11-13-15-17-19-21-23-24-25-26-27-28-30-32-34-36-38-40-42-44-46-48-58(67)78-54(51-75-57(66)47-45-43-41-39-37-35-33-31-29-22-20-18-16-14-12-10-8-6-4-2)52-76-81(71,72)80-82(73,74)77-53-55-59(68)60(69)61(79-55)65-50-49-56(63)64-62(65)70/h22,29,32,34,49-50,54-55,59-61,68-69H,3-21,23-28,30-31,33,35-48,51-53H2,1-2H3,(H,71,72)(H,73,74)(H2,63,64,70)/b29-22-,34-32-/t54-,55-,59-,60-,61-/m1/s1 |
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