Showing metabocard for MLCL(0:0/10:0/14:1(9Z)/28:1(11Z)) (MMDBc0056543)

Record Information
Version1.0
StatusDetected and Quantified
Creation Date2022-07-07 21:52:47 UTC
Update Date2022-08-14 02:54:36 UTC
MiMeDB IDMMDBc0056543
Metabolite Identification
Common NameMLCL(0:0/10:0/14:1(9Z)/28:1(11Z))
DescriptionMLCL(0:0/10:0/14:1(9Z)/28:1(11Z)) is a monolysocardiolipin (MLCL). Monolysocardiolipins have three fatty acid tails, instead of the usual two. MLCL(0:0/10:0/14:1(9Z)/28:1(11Z)) contains no chain at the C1 position, one decanoyl chain at the C2 position, one 9Z-tetradecenoyl chain at the C3 position, one 11Z-octacosanoyl chain at the C4 position. MLCL is present in eukaryotes as part of the metabolic cycle of mitochondrial lipids. Removal of one acyl chain from a cardiolipin results in generation of monolysocardiolipin (MLCL). MLCL has been used as an inter­mediate in the synthesis of spin-labeled CL to study the interaction of CL with mitochondrial enzymes. Because a role for MLCL has been suggested in apoptosis, this molecule has been used to study its interaction with various enzymes involved in lipid remodeling and apoptosis. There are two species of monolysocardiolipins, 1-MLCL which is missing a fatty acid in position R1 the and 2-MLCL which is missing a fatty acid in position R4.
Structure
MOLSDFPDBSMILESInChI

MOL for #<Metabolite:0x000055b76db22aa8>

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3D MOL for #<Metabolite:0x000055b76db22aa8>

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3D SDF for #<Metabolite:0x000055b76db22aa8>

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3D-SDF for #<Metabolite:0x000055b76db22aa8>

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PDB for #<Metabolite:0x000055b76db22aa8>

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3D PDB for #<Metabolite:0x000055b76db22aa8>

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SMILES for #<Metabolite:0x000055b76db22aa8>

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INCHI for #<Metabolite:0x000055b76db22aa8>

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Synonyms
ValueSource
[(2R)-3-({[(2R)-2-(decanoyloxy)-3-hydroxypropoxy](hydroxy)phosphoryl}oxy)-2-hydroxypropoxy][(2R)-2-[(11Z)-octacos-11-enoyloxy]-3-[(9Z)-tetradec-9-enoyloxy]propoxy]phosphinateGenerator
Chemical FormulaC61H116O16P2
Average Molecular Weight1167.531
Monoisotopic Molecular Weight1166.773861651
IUPAC NameNot Available
Traditional NameNot Available
CAS Registry NumberNot Available
SMILESNot Available
InChI Identifier
InChI=1S/C61H116O16P2/c1-4-7-10-13-16-18-20-21-22-23-24-25-26-27-28-29-30-31-32-33-35-37-40-43-46-49-61(66)77-58(53-71-59(64)47-44-41-39-36-34-19-17-14-11-8-5-2)55-75-79(69,70)73-52-56(63)51-72-78(67,68)74-54-57(50-62)76-60(65)48-45-42-38-15-12-9-6-3/h14,17,29-30,56-58,62-63H,4-13,15-16,18-28,31-55H2,1-3H3,(H,67,68)(H,69,70)/b17-14-,30-29-/t56-,57-,58-/m1/s1
InChI KeyCPCWPSMESOZAAD-SHZKTTPISA-N